Conservation of Amino Acids Through Evolution
• Their accession number was taken down and transferred to a master Word document
•The amino acid sequences of humans, mice, rats, sharks, frogs, birds, dogs, horses, and fish were all collected and put into a document.
•From there, the format was very particular, as Clustal Omega only recognizes the sequences if they are in a certain format.
•There would be a “>” symbol, followed by “ATM_ANIMAL_ACCESSIONNUMBER”
•* = completely identical : = minor differences . = some differences
•The other formats we looked at were the trees and the percentages.
•The trees are a visual representation of how all the ATM sequences align and how they are connected.
•The percentages represent how similar the sequences are to the human amino acid sequence.
We looked at three different types of results/data. Alignments, trees, and percentages. They were all mentioned in the video. Alignments represent conserved regions by using symbols. Trees use a visual representation to show how the sequences are connected, and the percentages give a number as to how similar the sequences are to the human amino acid sequence.